This Mac and Cheese Meatloaf Casserole is the ultimate comfort food mashup, combining a savory, BBQ-glazed meatloaf base with a creamy, cheesy layer of macaroni. It’s a hearty, all-in-one meal perfect for family dinners.

Mac and Cheese Meatloaf Casserole
Ingredients:
For the Meatloaf Layer Quantity
Ketchup 1 cup
Sweet Baby Ray’s Hickory & Brown Sugar Barbecue Sauce 1 cup
Lean Ground Beef 2 lbs
Ritz Crackers (crushed) 30
Lipton Onion Soup Mix (dry) 2 oz
Eggs 2
Salt 1 tsp
Pepper 1 tsp
Garlic Powder 1 tbsp
Onion Powder 1 tbsp
For the Mac and Cheese Layer:
Ingredient Quantity
Milk 2 cups
Condensed Cheddar Cheese Soup 10.5 oz
Macaroni Noodles 3 cups
Salt, Pepper, Garlic Powder, Onion Powder (use amount from meatloaf mix) To taste
Additional Cheese and Sauce:
Ingredient Quantity
Ketchup and Barbecue Sauce Mixture (remaining from step 2) Remaining 1/2 cup
Shredded Mozzarella and Cheddar Cheese Blend 4 cups (2 cups stirred into Mac & Cheese, 2 cups for topping)
How To Make Mac and Cheese Meatloaf Casserole:
Step 1: Preheat and Prepare: Preheat your oven to 350°F (175°C). Grease a 9×13 inch baking dish.
Step 2: Sweet and Tangy Sauce: In a medium bowl, whisk together the 1 cup ketchup and 1 cup barbecue sauce. You will use 1/2 cup now and 1/2 cup later.